who ordinal scale covid ?

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https://www.who.int/blueprint/priority-diseases/key-action/COVID-19_Treatment_Trial_Design_Master_Protocol_synopsis_Final_18022020.pdf

PDF WHO R&D Blueprint novel Coronavirus
https://www.who.int/blueprint/priority-diseases/key-action/COVID-19_Treatment_Trial_Design_Master_Protocol_synopsis_Final_18022020.pdf
post randomization. A special WHO committee arrived at the ordinal scale (given in the table below and the Appendix) that measures illness severity over time. The primary outcome could be a measure of patients’ clinical status at a particular time point after enrolment, depending upon frequency of outcome assessment (e.g., 14, 28, or 60 days). Agreement and consistency in recording

https://www.who.int/docs/default-source/documents/emergencies/minimalcoreoutcomemeasure.pdf

PDF A minimal common outcome measure set for COVID-19 clinical …
https://www.who.int/docs/default-source/documents/emergencies/minimalcoreoutcomemeasure.pdf
COVID-19 in the WHO International Clinical Trials Registry Platform.6 Although 41 different countries had registered clinical studies, 792 (69·8%) were based in China. The interventions varied and included antiviral drugs, mesenchymal stem cells, various immuno-modulatory drugs, corticosteroids, convalescent plasma,

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30483-7/fulltext

A minimal common outcome measure set for COVID-19 clinical …
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30483-7/fulltext
There are a number of ways that the WHO Clinical Progression Scale might be used to identify a population for study and to track the progress of patients with COVID-19 within clinical trials. At the time of trial randomisation, the scale can serve to identify an appropriate cohort for study. Vaccine trials could recruit patients with a score of 0 and use any progression across the scale as endpoints. Large studies of patients with mild disease could recruit patients with a score …

https://www.nature.com/articles/s41598-021-88509-9

An open-label randomized controlled trial evaluating the …
https://www.nature.com/articles/s41598-021-88509-9
The WHO 9-point ordinal scale is the most widely used scale to measure clinical progression outcome 12 in phase III RCTs involving patients with COVID-19, as in our study 31,32.

https://data.cochrane.org/concepts/o0M7jWjBe2h4e2

AssessmentScale – COVID-19 Ordinal Outcomes Scale
https://data.cochrane.org/concepts/o0M7jWjBe2h4e2
A Randomized, Controlled Clinical Trial to Test the Safety and Efficacy of Convalescent Donor Plasma to Treat COVID-19 in Hospitalized Adults. Male and Female Middle Aged 45-64 years Young Adult 19-24 years Aged 65-79 years Adult 19-44 years Aged 80 and over 80+ years COVID-19 Convalescent plasma Cellular and Gene Physiological or clinical …

https://rebelem.com/remdesivir-actt-1-adaptive-covid-19-treatment-trial-part-1/covid-19-ordinal-scale-of-clinical-improvement/

COVID-19 Ordinal Scale of Clinical Improvement – REBEL EM …

COVID-19 Ordinal Scale of Clinical Improvement

COVID-19 Ordinal Scale of Clinical Improvement.

https://www.nejm.org/doi/full/10.1056/NEJMoa2007764

Remdesivir for the Treatment of Covid-19 — Final Report | NEJM
https://www.nejm.org/doi/full/10.1056/NEJMoa2007764
Patients’ clinical status was assessed on an eight-category ordinal scale (defined below) and the National Early Warning Score (which includes six physiological measures; total scores range from …

https://apps.who.int/iris/rest/bitstreams/1278777/retrieve

This document is the update of an interim guidance …
https://apps.who.int/iris/rest/bitstreams/1278777/retrieve
Management of critical COVID-19: septic shock 25 11. Prevention of complications in hospitalized and critically ill patients with COVID19- 28 12. Antivirals, immunomodulators and other adjunctive therapies for COVID-19 30 13. Corticosteroid therapy and COVID-19 31 14. Treatment of other acute and chronic infections in patients with COVID-19 32

https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30147-4/fulltext

Endpoints used in phase III randomized controlled trials …
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30147-4/fulltext
For example, a commonly used 7-point ordinal scale was: 1. Death 2. Hospitalized, on invasive mechanical ventilation or Extracorporeal Membrane Oxygenation 3. Hospitalized, on non-invasive ventilation or high flow oxygen 4. Hospitalized, requiring low flow supplemental oxygen 5. Hospitalized, not requiring supplemental oxygen – requiring ongoing medical care (COVID-19 related or otherwise) 6. Hospitalized, not requiring supplemental oxygen – no longer required ongoing medical care …

https://www.aerzteblatt.de/nachrichten/117753/Primaerpraevention-Score-System-zur-COVID-19-Risiko-Einschaetzung

Primärprävention: Score-System zur COVID-19-Risiko …
https://www.aerzteblatt.de/nachrichten/117753/Primaerpraevention-Score-System-zur-COVID-19-Risiko-Einschaetzung
Primärprävention: Score-System zur COVID-19-Risiko-Ein­schätzung. Dienstag, 27. Oktober 2020. München – Wissenschaftler der Universität Erlangen-Nürnberg und der Ludwigs-Maximi­lians …